Blood glucose regulation using an open-loop insulin delivery system in pancreatectomized dogs given glucose infusions
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چکیده
منابع مشابه
Closed Loop Model for Glucose Insulin Regulation System Using Labview
Bio-Medical Instrumentation is an expanding and demanding area in which many fields are available to explore, among which diabetes is a main segment to address. Glucose and Insulin are both interrelated terms. Glucose is a sugar which provides energy to the cells. Insulin is a hormone which supports the absorption of glucose. The Glucose-Insulin regulation model is obtained by modifying the dyn...
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OBJECTIVE Attempts to build an artificial pancreas by using subcutaneous insulin delivery from a portable pump guided by an subcutaneous glucose sensor have encountered delays and variability of insulin absorption. We tested closed-loop intraperitoneal insulin infusion from an implanted pump driven by an subcutaneous glucose sensor via a proportional-integral-derivative (PID) algorithm. RESEA...
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High-dose intravenous infusion of 5% glucose promotes rebound hypoglycaemia and hypovolaemia in healthy volunteers. To study whether such effects occur in response to glucose/insulin, 12 healthy firemen (mean age, 39 years) received three infusions over 1-2 h that contained 20 ml of 2.5% glucose/kg of body weight, 5 ml of 10% glucose/kg of body weight with 0.05 unit of rapid-acting insulin/kg o...
متن کاملEffect of Insulin - Glucose Infusions on Plasma
This work was presented in part at the Southern Section, American Federation for Clinical Research, New Orleans, La., 1 February 1975, and the American Diabetes Association, New York, 17 June 1975. Dr. Raskin is a Veterans Administration Research Associate. Dr. Fujita's present address is the Fourth Department of Internal Medicine, The Jikei University School of Medicine, Minato-ku, Tokyo, Japa...
متن کاملNormalization of blood glucose in totally pancreatectomized dogs by use of pancreatic chambers.
Two pancreatic chambers constructed of plastic tube and ultrafiltration membrane and containing the minced pancreases of five neonatal rats were implanted in the omentum of totally pancreatectomized diabetic dogs. Blood glucose levels in the diabetic dogs leveled off just after operation, in contrast with those in control animals, in which vacant chambers were implanted, and began to decrease a...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1979
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf01225463